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Journal of Veterinary Diagnostic Investigation, Vol 17, Issue 6, 594-597
Copyright © 2005 by American Association of Veterinary Laboratory Diagnosticians

Case Reports

Persistent viral shedding during asymptomatic Aleutian mink disease parvoviral infection in a ferret

KE Pennick, MA Stevenson, KS Latimer, BW Ritchie, and CR Gregory

Department of Pathology, University of Georgia College of Veterinary Medicine, Athens 30602, USA.

A 2-year-old domestic ferret that appeared clinically healthy was repeatedly seropositive for Aleutian mink disease parvovirus (ADV) over a 2-year observation period. Antibody titers, determined by counter-immunoelectrophoresis, ranged from 1024 to 4096. Viral DNA also was identified in serum, urine, feces, and blood cell fractions by polymerase chain reaction analysis. Ultimately, DNA in situ hybridization revealed ADV DNA in histologic sections of various tissues and organs. These data indicate that this asymptomatic ferret was persistently infected with ADV.


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