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Journal of Veterinary Diagnostic Investigation Vol. 20 Issue 5, 656-660
Copyright © 2008 by the American Association of Veterinary Laboratory Diagnosticians
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Case Reports

Diffuse intestinal T-cell lymphosarcoma in a yellow-naped Amazon parrot (Amazona ochrocephala auropalliata)

Marcy J. Souza, Shelley J. Newman, Cheryl B. Greenacre, James S. Avenell, Jonathan S. Wall, Jeffrey C. Phillips, Michael M. Fry, Robert L. Donnell and Gregory B. Daniel1

Correspondence: 1Corresponding Author: Marcy J. Souza, Department of Comparative Medicine College of Veterinary Medicine, 2407 River Road, University of Tennessee, Knoxville, TN 37996. msouza{at}utk.edu

A 10-year-old, intact, female yellow-naped Amazon parrot was examined because of anemia, lymphocytic leukocytosis, regurgitation, and weight loss. A positive fecal occult blood and monoclonal globulinopathy were present. A distended proventriculus and diffusely thickened loops of small intestine with irregular luminal surfaces were identified with contrast radiography and contrast computed tomography. A micro positron emission tomography scan was performed with 18F-fluorodeoxyglucose. Diffuse intestinal T-cell lymphosarcoma was diagnosed based on histopathology and immunohistochemistry of full thickness small intestinal biopsies. The patient was treated with a multidrug chemotherapy protocol with little to no effect. Euthanasia was elected, and intestinal lymphosarcoma was confirmed on histopathology of necropsy intestinal samples; no other organs demonstrated neoplastic infiltration. To the authors' knowledge, no reports are currently available detailing the clinical presentation or diagnosis of diffuse intestinal T-cell lymphosarcoma in any avian species.

Key Words: Avian • immunohistochemistry • lymphosarcoma • positron emission tomography






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